Blocking of TLR2 or TLR4 before mycobacterial infection of main epithelial cells non-significantly restored the NF-kB values to qualifications stages
TLR4 blocking final results in cytoplasmic CREB aggregation. Mycobacterial modulation of TLR signalling pathways was confirmed by immuno-fluorescence staining of pCREB and NF-kB expression in primary epithelial cells. (a) Mycobacterial…