Drug resistance mutations influence the measurement of plasma HIV-RNA by different viral load techniques AIDS Patient Care STDS 17:321324. 38. Pyne MT, Konnick EQ, Phansalkar A, Hillyard DR Evaluation of the Abbott investigational use only realtime HIV-1 assay and comparison to the Roche Amplicor HIV-1 monitor test, version 1.5. J Mol Diagn 11:1485-00-3 347354. 39. Ruelle J, Jnaoui K, Lefevre I, Lamarti N, Goubau N Comparative evaluation of the VERSANT HIV-1 RNA 1.0 kinetic PCR molecular system for the quantification of HIV-1 plasma viral load. J Clin Virol 44:297 301. 8 Systematic Review of Viral Load Technologies 40. Schutten M, Fries E, Burghoorn-Maas C, Niesters HGM Evaluation of the analytical performance of the new Abbott RealTime RT-PCRs for the quantitative detection of HCV and HIV-1 RNA. J Clin Virol 40:99104. 41. Scott LE, Noble LD, Moloi J, Erasmus L, Venter WDF, et al. Evaluation of the Abbott m2000 RealTime human immunodeficiency virus type 1 assay for HIV load monitoring in South Africa compared to the Roche 15481974 Cobas AmpliPrep-Cobas Amplicor, Roche Cobas AmpliPrep-Cobas TaqMan HIV-1, and BioMerieux NucliSENS EasyQ HIV-1 assays. J Clin Microbiol 47:2209 2217. 42. Sire J-M, Vray M, Merzouk M, Plantier J-C, Pavie J, et al. Comparative RNA quantification of HIV-1 group M and non-M with the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 v2.0 and Abbott Real-Time HIV-1 PCR assays. J Acquir Immune Defic Syndr 56:239243. 43. Sivapalasingam S, Wangechi B, Marshed F, Laverty M, Essajee S, et al. Monitoring virologic ML-240 chemical information responses to antiretroviral therapy in HIV-infected adults in Kenya: Evaluation of a low-cost viral load assay. PLoS ONE 4. 44. Sizmann D, Glaubitz J, Simon CO, Goedel S, Buergisser P, Drogan D, et al. Improved HIV-1 RNA quantitation by COBAS AmpliPrep/COBAS TaqMan HIV-1 Test, v2.0 using a novel dual-target approach. J Clin Virol 49:4146. 45. Sloma CR, Germer JJ, Gerads TM, Mandrekar JN, Mitchell PS, et al. Comparison of the Abbott realtime human immunodeficiency virus type 1 assay to the Cobas AmpliPrep/Cobas TaqMan HIV-1 test: workflow, reliability, and direct costs. J Clin Microbiol 47:889895. 46. Ssebugenyi I, Kizza A, Mpoza B, Aluma G, Boaz I, et al. Comparison of the Abbott m2000 HIV-1 real-time and Roche AMPLICOR monitor v1.5 HIV1 assays on plasma specimens from Rakai, Uganda. Int J STD AIDS 22:373 375. 47. Stevens W, Horsfield P, Scott LE Evaluation of the Performance of the Automated NucliSENS easyMAG and EasyQ Systems versus the Roche AmpliPrep-AMPLICOR Combination for High-Throughput Monitoring of Human Immunodeficiency Virus Load. J Clin Microbiol 45:12441249. 48. Swanson P, Huang S, Abravaya K, de Mendoza C, Soriano V, et al. Evaluation of performance across the dynamic range of the Abbott RealTime 49. 50. 51. 52. 53. 54. 55. 56. HIV-1 assay as compared to VERSANT HIV-1 RNA 3.0 and AMPLICOR HIV-1 MONITOR v1.5 using serial dilutions of 39 group M and O viruses. J Virol Methods 141:4957. Tang N, Huang S, Salituro J, Mak W-B, Cloherty G, et al. A RealTime HIV-1 viral load assay for automated quantitation of HIV-1 RNA in genetically diverse group M subtypes A-H, group O and group N samples. J Virol Methods 146:236245. Troppan KT, Stelzl E, Violan D, Winkler M, Kessler HH Evaluation of the new VERSANT HIV-1 RNA 1.0 Assay for quantitative detection of human immunodeficiency virus type 1 RNA. J Clin Virol 46:6974. van Rensburg EJ, Tait K, Watt A, Schall R Comparative evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 version.Drug resistance mutations influence the measurement of plasma HIV-RNA by different viral load techniques AIDS Patient Care STDS 17:321324. 38. Pyne MT, Konnick EQ, Phansalkar A, Hillyard DR Evaluation of the Abbott investigational use only realtime HIV-1 assay and comparison to the Roche Amplicor HIV-1 monitor test, version 1.5. J Mol Diagn 11:347354. 39. Ruelle J, Jnaoui K, Lefevre I, Lamarti N, Goubau N Comparative evaluation of the VERSANT HIV-1 RNA 1.0 kinetic PCR molecular system for the quantification of HIV-1 plasma viral load. J Clin Virol 44:297 301. 8 Systematic Review of Viral Load Technologies 40. Schutten M, Fries E, Burghoorn-Maas C, Niesters HGM Evaluation of the analytical performance of the new Abbott RealTime RT-PCRs for the quantitative detection of HCV and HIV-1 RNA. J Clin Virol 40:99104. 41. Scott LE, Noble LD, Moloi J, Erasmus L, Venter WDF, et al. Evaluation of the Abbott m2000 RealTime human immunodeficiency virus type 1 assay for HIV load monitoring in South Africa compared to the Roche 15481974 Cobas AmpliPrep-Cobas Amplicor, Roche Cobas AmpliPrep-Cobas TaqMan HIV-1, and BioMerieux NucliSENS EasyQ HIV-1 assays. J Clin Microbiol 47:2209 2217. 42. Sire J-M, Vray M, Merzouk M, Plantier J-C, Pavie J, et al. Comparative RNA quantification of HIV-1 group M and non-M with the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 v2.0 and Abbott Real-Time HIV-1 PCR assays. J Acquir Immune Defic Syndr 56:239243. 43. Sivapalasingam S, Wangechi B, Marshed F, Laverty M, Essajee S, et al. Monitoring virologic responses to antiretroviral therapy in HIV-infected adults in Kenya: Evaluation of a low-cost viral load assay. PLoS ONE 4. 44. Sizmann D, Glaubitz J, Simon CO, Goedel S, Buergisser P, Drogan D, et al. Improved HIV-1 RNA quantitation by COBAS AmpliPrep/COBAS TaqMan HIV-1 Test, v2.0 using a novel dual-target approach. J Clin Virol 49:4146. 45. Sloma CR, Germer JJ, Gerads TM, Mandrekar JN, Mitchell PS, et al. Comparison of the Abbott realtime human immunodeficiency virus type 1 assay to the Cobas AmpliPrep/Cobas TaqMan HIV-1 test: workflow, reliability, and direct costs. J Clin Microbiol 47:889895. 46. Ssebugenyi I, Kizza A, Mpoza B, Aluma G, Boaz I, et al. Comparison of the Abbott m2000 HIV-1 real-time and Roche AMPLICOR monitor v1.5 HIV1 assays on plasma specimens from Rakai, Uganda. Int J STD AIDS 22:373 375. 47. Stevens W, Horsfield P, Scott LE Evaluation of the Performance of the Automated NucliSENS easyMAG and EasyQ Systems versus the Roche AmpliPrep-AMPLICOR Combination for High-Throughput Monitoring of Human Immunodeficiency Virus Load. J Clin Microbiol 45:12441249. 48. Swanson P, Huang S, Abravaya K, de Mendoza C, Soriano V, et al. Evaluation of performance across the dynamic range of the Abbott RealTime 49. 50. 51. 52. 53. 54. 55. 56. HIV-1 assay as compared to VERSANT HIV-1 RNA 3.0 and AMPLICOR HIV-1 MONITOR v1.5 using serial dilutions of 39 group M and O viruses. J Virol Methods 141:4957. Tang N, Huang S, Salituro J, Mak W-B, Cloherty G, et al. A RealTime HIV-1 viral load assay for automated quantitation of HIV-1 RNA in genetically diverse group M subtypes A-H, group O and group N samples. J Virol Methods 146:236245. Troppan KT, Stelzl E, Violan D, Winkler M, Kessler HH Evaluation of the new VERSANT HIV-1 RNA 1.0 Assay for quantitative detection of human immunodeficiency virus type 1 RNA. J Clin Virol 46:6974. van Rensburg EJ, Tait K, Watt A, Schall R Comparative evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 version.