Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This article is distributed below the terms from the Creative Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution with the function without having further permission supplied the original perform is attributed as specified around the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).2 water content, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and an increase in the frequency of bowel movements to 3 stools every day have GR79236 web normally been used as a definition for epidemiological investigations. Depending on a community-based study point of view, diarrhea is defined as no less than 3 or much more loose stools within a 24-hour period.12 A diarrheal episode is considered because the passage of three or additional loose or liquid stools in 24 hours prior to presentation for care, which is regarded as essentially the most practicable in children and adults.13 Nevertheless, prolonged and persistent diarrhea can last among 7 and 13 days and at least 14 days, respectively.14,15 The disease is hugely sensitive to climate, displaying seasonal variations in several internet sites.16 The climate sensitivity of diarrheal illness is consistent with observations with the direct effects of climate variables on the causative agents. Temperature and relative humidity possess a direct influence on the price of replication of bacterial and protozoan pathogens and on the survival of enteroviruses in the environment.17 Wellness care journal.pone.0169185 seeking is Filgotinib recognized to become a result of a complicated behavioral approach that is certainly influenced by various factors, such as socioeconomic and demographic and traits, perceived need to have, accessibility, and service availability.Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This article is distributed below the terms with the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution of the work with no additional permission provided the original perform is attributed as specified around the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).two water content, volume, or frequency of stools.11 A reduce in consistency (ie, soft or liquid) and a rise within the frequency of bowel movements to 3 stools per day have typically been utilised as a definition for epidemiological investigations. Determined by a community-based study viewpoint, diarrhea is defined as no less than three or extra loose stools within a 24-hour period.12 A diarrheal episode is deemed as the passage of three or extra loose or liquid stools in 24 hours prior to presentation for care, that is regarded as one of the most practicable in children and adults.13 On the other hand, prolonged and persistent diarrhea can final between 7 and 13 days and a minimum of 14 days, respectively.14,15 The disease is very sensitive to climate, displaying seasonal variations in quite a few internet sites.16 The climate sensitivity of diarrheal illness is consistent with observations from the direct effects of climate variables on the causative agents. Temperature and relative humidity have a direct influence around the rate of replication of bacterial and protozoan pathogens and around the survival of enteroviruses within the atmosphere.17 Wellness care journal.pone.0169185 in search of is recognized to become a result of a complicated behavioral approach that is certainly influenced by quite a few components, which includes socioeconomic and demographic and qualities, perceived need, accessibility, and service availability.