N American Retrospective Retrospective African American RetrospectiveGil,ColorectalKrupa,LarynxAgalliu,ProstateAgalliu,ProstateRajaraman,Braibbasi,LarynxHan,BreastJoshi,ColorectalChang,LungHung,LungMcWilliam,PancreaticRajaraman,BreastSmith,BreastSmith,BreastCrew,BreastJorgensen,BreastHuang,ColorectalMechanic,BreastMechanic,BreastMoreno,ColorectalSmith,BreastXPFrs (SerSer)SNPlex, SPshot, Quantitative PCR, PCRRFLPDoherty,EndometrialRoberts,BreastAgalliu,ProstateAgalliu,ProstateWang,BladderHooker,ProstateXPF Variants and Cancer RiskPovey,Melanoma A single a single.orgEthnicity Caucasian Asian Caucasian Asian Retrospective PB.. Retrospective HB.. Retrospective HB.. Blood buffy coats Sputum Retrospective HB. Study PubMed ID:http://jpet.aspetjournals.org/content/185/3/438 type Source of manage Cases Controls MAF of controlsTable. Cont.Very first author, Year Spain Korea UK USACancer type CountryPaPowerbSource of DGenotyping methodsGarciaClosas,Bladderleukocytes, mouthwash Pooled sample DASH Hybaid Pooled Quantitative PCRLee,BreastMatullo,BladderShen,LungXPFrs (SerPro)USA USA Spain USA USA Caucasian Retrospective PB. African American Retrospective PB. Caucasian Retrospective HB.. African American Retrospective HB. Caucasian Retrospective HB…. Blood Blood Quantitative PCR MassARRAY leukocytes, mouthwash Pooled sample Lymphocytes Lymphocytes Quantitative PCR, Sequencing Quantitative PCR, SequencingRajaraman,BrainHooker,ProstateChi Multicenter Caucasian Multicenter African Multicenter Asian Retrospective PB,HB 
Retrospective PB,HB Retrospective PB,HB Asian Retrospective HB..GarciaClosas,BladderMechanic,BreastMechanic,BreastXPFrs (intron)… Blood Pooled Pooled Pooled PCRRFLP Quantitative PCR Quantitative PCR Quantitative PCRWang,BladderGaudet,BreastGaudet,BreastGaudet,BreastAbbreviation: SNP, single nucleotide polymorphism; HB, Hospital primarily based; PB, Population primarily based; FB, Family primarily based; RFLP, Restriction fragment length polymorphisms. a P worth for domint genetic model inside the associations with XPF polymorphisms. b Statistical power to detect an OR of. (or..).ponetXPF Variants and Cancer RiskTable. Metaalysis of the associations among XPF polymorphisms and cancer risk below the XP recessive genetic model.Variables OR ( CI)a het a hetNo. of CasesControlsHomozygous modelRecessive modelPowerbstudies AA vs. GG. ().. (). AA vs. (AG + GG).POR ( CI)PIPPIrs (ArgGln)All.Cancer sort. (). (). (). (). (). (). (). (). ().. (). ().. ()…. ().. (). ().. (). ().. ()………. 1 a single.org. ()..().(). ().. (). (). (). ()…… (). ().. ()… (). (). ()….. CC vs. TT. ().. (). ().. ()…. (). (). () CC vs. (CT + TT). ()……… (). (). (). (). ()……. (). (). (). (). ()………BreastColorectalHead Triptorelin chemical information neckOthersLungProstateBrainEndometrialPancreaticEthnicityCaucasiafrican AmericanLatinoMixedSource of controlsPBHBPBHBSample sizers (SerSer)AllCancer typeProstateBladderBreastOthersXPF Variants and Cancer RiskMelanomaTable. Cont.Variables OR ( CI)a hetNo. of CasesControlsHomozygous modelRecessive modelPowerb One SPDB site particular one.orgPOR ( CI) AA vs. (AG + GG).. (). ()..studies AA vs. GG. (). ()PIPPa hetIrs (ArgGln)LungEndometrialEthnicity. ()… (). ().. (). ().. ()……Caucasiafrican AmericasianSource of controls. ().. ().. (). ()….PB CC vs. TT GG vs. CC. ().. ().. ().. ()… ()..HBSample size. (). (). () CC vs. (CT + TT). () GG vs. (CG + CC). ()………rs (SerPro)Allrs (intron)AllAbbreviation: HB, Hospital based; PB, Population primarily based; FB, Family primarily based. The results had been in bold, if the CI excluded or P, a P value for heterogeneity test. b Statis.N American Retrospective Retrospective African American RetrospectiveGil,ColorectalKrupa,LarynxAgalliu,ProstateAgalliu,ProstateRajaraman,Braibbasi,LarynxHan,BreastJoshi,ColorectalChang,LungHung,LungMcWilliam,PancreaticRajaraman,BreastSmith,BreastSmith,BreastCrew,BreastJorgensen,BreastHuang,ColorectalMechanic,BreastMechanic,BreastMoreno,ColorectalSmith,BreastXPFrs (SerSer)SNPlex, SPshot, Quantitative PCR, PCRRFLPDoherty,EndometrialRoberts,BreastAgalliu,ProstateAgalliu,ProstateWang,BladderHooker,ProstateXPF Variants and Cancer RiskPovey,Melanoma 1 one.orgEthnicity Caucasian Asian Caucasian Asian Retrospective PB.. Retrospective HB.. Retrospective HB.. Blood buffy coats Sputum Retrospective HB. Study PubMed ID:http://jpet.aspetjournals.org/content/185/3/438 variety Source of control Circumstances Controls MAF of controlsTable. Cont.Initial author, Year Spain Korea UK USACancer sort CountryPaPowerbSource of DGenotyping methodsGarciaClosas,Bladderleukocytes, mouthwash Pooled sample DASH Hybaid Pooled Quantitative PCRLee,BreastMatullo,BladderShen,LungXPFrs (SerPro)USA USA Spain USA USA Caucasian Retrospective PB. African American Retrospective PB. Caucasian Retrospective HB.. African American Retrospective HB. Caucasian Retrospective HB…. Blood Blood Quantitative PCR MassARRAY leukocytes, mouthwash Pooled sample Lymphocytes Lymphocytes Quantitative PCR, Sequencing Quantitative PCR, SequencingRajaraman,BrainHooker,ProstateChi Multicenter Caucasian Multicenter African Multicenter Asian Retrospective PB,HB Retrospective PB,HB Retrospective PB,HB Asian Retrospective HB..GarciaClosas,BladderMechanic,BreastMechanic,BreastXPFrs (intron)… Blood Pooled Pooled Pooled PCRRFLP Quantitative PCR Quantitative PCR Quantitative PCRWang,BladderGaudet,BreastGaudet,BreastGaudet,BreastAbbreviation: SNP, single nucleotide polymorphism; HB, Hospital based; PB, Population based; FB, Household primarily based; RFLP, Restriction fragment length polymorphisms. a P worth for domint genetic model within the associations with XPF polymorphisms. b Statistical energy to detect an OR of. (or..).ponetXPF Variants and Cancer RiskTable. Metaalysis with the associations between XPF polymorphisms and cancer danger under the XP recessive genetic model.Variables OR ( CI)a het a hetNo. of CasesControlsHomozygous modelRecessive modelPowerbstudies AA vs. GG. ().. (). AA vs. (AG + GG).POR ( CI)PIPPIrs (ArgGln)All.Cancer type. (). (). (). (). (). (). (). (). ().. (). ().. ()…. ().. (). ().. (). ().. ()………. One 1.org. ()..().(). ().. (). (). (). ()…… (). ().. ()… (). (). ()….. CC vs. TT. ().. (). ().. ()…. (). (). () CC vs. (CT + TT). ()……… (). (). (). (). ()……. (). (). (). (). ()………BreastColorectalHead neckOthersLungProstateBrainEndometrialPancreaticEthnicityCaucasiafrican AmericanLatinoMixedSource of controlsPBHBPBHBSample sizers (SerSer)AllCancer typeProstateBladderBreastOthersXPF Variants and Cancer RiskMelanomaTable. Cont.Variables OR ( CI)a hetNo. of CasesControlsHomozygous modelRecessive modelPowerb 1 a single.orgPOR ( CI) AA vs. (AG + GG).. (). ()..studies AA vs. GG. (). ()PIPPa hetIrs (ArgGln)LungEndometrialEthnicity. ()… (). ().. (). ().. ()……Caucasiafrican AmericasianSource of controls. ().. ().. (). ()….PB CC vs. TT GG vs. CC. ().. ().. ().. ()… ()..HBSample size. (). (). () CC vs. (CT 
+ TT). () GG vs. (CG + CC). ()………rs (SerPro)Allrs (intron)AllAbbreviation: HB, Hospital based; PB, Population based; FB, Loved ones based. The outcomes were in bold, when the CI excluded or P, a P value for heterogeneity test. b Statis.