Ive years [35]. Parental education was determined according to the maximum education level/degree, including the following answers: elementary college, high college, college degree, and university degree. Parental/familial conflict was assessed using the query “How normally do you have got a conflict with your parents/family”, with the following achievable answers: under no circumstances, hardly ever, from time to time, and frequently [26]. 2.three. Statistical Analyses The normality of the distribution was checked making use of Kolmogorov mirnov’s test, along with the descriptive statistics included means and typical deviations (for numerical variables), and frequencies and percentages (for ordinal and nominal variables). The differences among the groups had been evidenced by the Mann hitney Z test (MW) (for ordinal variables), and Chi square (two ). Spearman’s rank order correlation was calculated so as to evidence the associations in between age and PAL at the baseline and follow-up. The T-test for dependent samples was made use of to identify the changes in PAL among the baseline (pre-pandemic period) and Icosabutate In Vivo follow-up (lockdown period). Logistic regression (with an Odds Ratio (OR) plus a 95 Self-confidence Interval (95 CI) presented) was applied to show the association among the predictors plus the categorized PAL (Oprozomib Autophagy insufficient PAL, coded as “1” vs. sufficient PAL, coded as “2”) at the baseline and follow-up. Also, as a way to determine any current association among the predictors and adjustments that occurred in PAL, we calculated the logistic regression with dichotomized PAL as a criterion (low-risk group, coded as “1”, vs. high-risk group, coded as “2”). Mainly because preliminary analyses showed important associations among age, sport participation, parental/familial conflict, parental education and Gender with PAL (please see the outcomes Section for a lot more details), the logistic regressions have been controlled for confounders (age, sport participation, male gender, parental education, and parental/familial conflict). A p-Value of 95 was applied, and the Statistica ver. 13.5 statistical package (Tibco Inc., Palo Alto, CA, USA was utilised for all of the calculations. three. Outcomes Descriptive statistics (frequencies and percentages) in the studied variables for the total sample are presented in Supplementary Table S1. The PAL drastically declined among the baseline and follow-up (two.43 0.71 and two.00 0.75, respectively; t-test = four.14, p 0.001), indicating a adverse impact on the COVID-19-imposed lockdown on PAL among the studied adolescents. The variations involving the groups of adolescents based on sufficient/insufficient PAL at the baseline are presented in Table 1. The enough PAL was more prevalent amongst boys (2 = 70.01, p 0.01), these adolescents who had been involved in sports (MW = 7.89, p 0.001), adolescents whose parents were better educated (MW = three.69, p 0.001), and those who reported a lower level of conflict with their parents/family (MW = 4.64, p 0.01). Scholastic components didn’t differentiate the groups clustered as outlined by PAL sufficiency/insufficiency in the baseline.Table 1. Descriptive statistics (F–frequencies; –percentages) for the study variables, with variations among groups in accordance with the insufficiency/sufficiency with the physical activity levels (PAL) at the baseline (MW–Mann hitney test; two –Chi square test). Insufficient PAL F Gender Male Female MissingSufficient PAL F 142 38 0 78.89 21.11 0.00 Z/MW/2 p40.00 58.59 1.142 20870.0.Youngsters 2021, eight,six ofTable 1. Con.