Product Name :
N-Boc-N-bis(PEG4-OH)
Description:
N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
2093154-01-7
Molecular Weight:
469.57
Formula:
C21H43NO10
Chemical Name:
tert-butyl N,N-bis(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl)carbamate
Smiles :
CC(C)(C)OC(=O)N(CCOCCOCCOCCO)CCOCCOCCOCCO
InChiKey:
KKRPLRNWLDABDZ-UHFFFAOYSA-N
InChi :
InChI=1S/C21H43NO10/c1-21(2,3)32-20(25)22(4-8-26-12-16-30-18-14-28-10-6-23)5-9-27-13-17-31-19-15-29-11-7-24/h23-24H,4-19H2,1-3H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Hispidulin} site|{Hispidulin} JAK/STAT Signaling|{Hispidulin} Protocol|{Hispidulin} In stock|{Hispidulin} custom synthesis|{Hispidulin} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.{{DOTMA} site|{DOTMA} Metabolic Enzyme/Protease|{DOTMA} Technical Information|{DOTMA} In Vivo|{DOTMA} custom synthesis|{DOTMA} Autophagy} N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).PMID:23546012 |Product information|CAS Number: 2093154-01-7|Molecular Weight: 469.57|Formula: C21H43NO10|Chemical Name: tert-butyl N,N-bis(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl)carbamate|Smiles: CC(C)(C)OC(=O)N(CCOCCOCCOCCO)CCOCCOCCOCCO|InChiKey: KKRPLRNWLDABDZ-UHFFFAOYSA-N|InChi: InChI=1S/C21H43NO10/c1-21(2,3)32-20(25)22(4-8-26-12-16-30-18-14-28-10-6-23)5-9-27-13-17-31-19-15-29-11-7-24/h23-24H,4-19H2,1-3H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|