Wed. Feb 5th, 2025

Product Name :
Duloxetine-d7

Description:
Duloxetine-d7 ((S)-Duloxetine-d7) is the deuterium labeled Duloxetine. Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).

CAS:
919514-01-5

Molecular Weight:
304.46

Formula:
C18H19NOS

Chemical Name:
methyl[(3S)-3-[(2,3,4,5,6,7,8-²H₇)naphthalen-1-yloxy]-3-(thiophen-2-yl)propyl]amine

Smiles :
[2H]C1=C(O[C@@H](CCNC)C2=CC=CS2)C2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])=C1[2H]

InChiKey:
ZEUITGRIYCTCEM-KGAVXYHHSA-N

InChi :
InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1/i2D,3D,4D,6D,7D,8D,9D

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Duloxetine-d7 ((S)-Duloxetine-d7) is the deuterium labeled Duloxetine. Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).|Product information|CAS Number: 919514-01-5|Molecular Weight: 304.46|Formula: C18H19NOS|Chemical Name: methyl[(3S)-3-[(2,3,4,5,6,7,8-²H₇)naphthalen-1-yloxy]-3-(thiophen-2-yl)propyl]amine|Smiles: [2H]C1=C(O[C@@H](CCNC)C2=CC=CS2)C2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])=C1[2H]|InChiKey: ZEUITGRIYCTCEM-KGAVXYHHSA-N|InChi: InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1/i2D,3D,4D,6D,7D,8D,9D|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Epalrestat} medchemexpress|{Epalrestat} Metabolic Enzyme/Protease|{Epalrestat} Technical Information|{Epalrestat} References|{Epalrestat} custom synthesis|{Epalrestat} Cancer} |Shelf Life: ≥12 months if stored properly.{{Bisacodyl} medchemexpress|{Bisacodyl} Neuronal Signaling|{Bisacodyl} Protocol|{Bisacodyl} Description|{Bisacodyl} supplier|{Bisacodyl} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24883330 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.|Products are for research use only. Not for human use.|

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