Mon. Dec 30th, 2024

Product Name :
Jacobine

Description:
Jacobine is a pyrrolizidine alkaloid (PA) from Senecio jacobaea. Jacobine is active against second instar larvae of thrips.

CAS:
6870-67-3

Molecular Weight:
351.39

Formula:
C18H25NO6

Chemical Name:
(2S, 3S, 5’R, 6’R, 9a1’R, 14a’R)-6′-hydroxy-3, 5′, 6′-trimethyl-5′, 6′, 9′, 9a1′, 11′, 13′, 14′, 14a’-octahydro-2’H-spiro[oxirane-2, 3′-[1, 6]dioxacyclododecino[2, 3, 4-gh]pyrrolizine]-2′, 7′(4’H)-dione

Smiles :
C[C@@]1(O)[C@H](C)C[C@@]2(O[C@H]2C)C(=O)O[C@@H]2CCN3CC=C(COC1=O)[C@@H]32

InChiKey:
IAPHXJRHXBQDQJ-WKMWQDDRSA-N

InChi :
InChI=1S/C18H25NO6/c1-10-8-18(11(2)25-18)16(21)24-13-5-7-19-6-4-12(14(13)19)9-23-15(20)17(10,3)22/h4,10-11,13-14,22H,5-9H2,1-3H3/t10-,11+,13-,14-,17-,18+/m1/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Jacobine is a pyrrolizidine alkaloid (PA) from Senecio jacobaea.{{Gefitinib} site|{Gefitinib} Apoptosis|{Gefitinib} Technical Information|{Gefitinib} In stock|{Gefitinib} manufacturer|{Gefitinib} Autophagy} Jacobine is active against second instar larvae of thrips.|Product information|CAS Number: 6870-67-3|Molecular Weight: 351.39|Formula: C18H25NO6|Chemical Name: (2S, 3S, 5’R, 6’R, 9a1’R, 14a’R)-6′-hydroxy-3, 5′, 6′-trimethyl-5′, 6′, 9′, 9a1′, 11′, 13′, 14′, 14a’-octahydro-2’H-spiro[oxirane-2, 3′-[1, 6]dioxacyclododecino[2, 3, 4-gh]pyrrolizine]-2′, 7′(4’H)-dione|Smiles: C[C@@]1(O)[C@H](C)C[C@@]2(O[C@H]2C)C(=O)O[C@@H]2CCN3CC=C(COC1=O)[C@@H]32|InChiKey: IAPHXJRHXBQDQJ-WKMWQDDRSA-N|InChi: InChI=1S/C18H25NO6/c1-10-8-18(11(2)25-18)16(21)24-13-5-7-19-6-4-12(14(13)19)9-23-15(20)17(10,3)22/h4,10-11,13-14,22H,5-9H2,1-3H3/t10-,11+,13-,14-,17-,18+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Emodepside} site|{Emodepside} Anti-infection|{Emodepside} Protocol|{Emodepside} In Vitro|{Emodepside} manufacturer|{Emodepside} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.PMID:23833812 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Pyrrolizidine alkaloids (PAs) at plant concentration reduce thrips survival on average with 21%. Structurally related PAs affect survival of thrips differently. PA free bases reduce thrips survival more than the corresponding PA N-oxides.|Products are for research use only. Not for human use.|

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