Product Name :
Lomeguatrib
Description:
Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment.
CAS:
192441-08-0
Molecular Weight:
326.17
Formula:
C10H8BrN5OS
Chemical Name:
6-[(4-bromothiophen-2-yl)methoxy]-7H-purin-2-amine
Smiles :
NC1=NC(OCC2=CC(Br)=CS2)=C2NC=NC2=N1
InChiKey:
JUJPKFNFCWJBCX-UHFFFAOYSA-N
InChi :
InChI=1S/C10H8BrN5OS/c11-5-1-6(18-3-5)2-17-9-7-8(14-4-13-7)15-10(12)16-9/h1,3-4H,2H2,(H3,12,13,14,15,16)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment.|Product information|CAS Number: 192441-08-0|Molecular Weight: 326.17|Formula: C10H8BrN5OS|Chemical Name: 6-[(4-bromothiophen-2-yl)methoxy]-7H-purin-2-amine|Smiles: NC1=NC(OCC2=CC(Br)=CS2)=C2NC=NC2=N1|InChiKey: JUJPKFNFCWJBCX-UHFFFAOYSA-N|InChi: InChI=1S/C10H8BrN5OS/c11-5-1-6(18-3-5)2-17-9-7-8(14-4-13-7)15-10(12)16-9/h1,3-4H,2H2,(H3,12,13,14,15,16)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Fluvoxamine} site|{Fluvoxamine} Neuronal Signaling|{Fluvoxamine} Technical Information|{Fluvoxamine} Formula|{Fluvoxamine} supplier|{Fluvoxamine} Epigenetics} |Shelf Life: ≥360 days if stored properly.{{TCEP} web|{TCEP} Activator|{TCEP} Technical Information|{TCEP} References|{TCEP} custom synthesis} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23546012 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|