Product Name :
Laninamivir
Description:
Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively.
CAS:
203120-17-6
Molecular Weight:
346.34
Formula:
C13H22N4O7
Chemical Name:
(2R,3R,4S)-4-[(diaminomethylidene)amino]-2-[(1R,2R)-2,3-dihydroxy-1-methoxypropyl]-3-acetamido-3,4-dihydro-2H-pyran-6-carboxylic acid
Smiles :
CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](OC)[C@H](O)CO)C(O)=O)N=C(N)N
InChiKey:
QNRRHYPPQFELSF-CNYIRLTGSA-N
InChi :
InChI=1S/C13H22N4O7/c1-5(19)16-9-6(17-13(14)15)3-8(12(21)22)24-11(9)10(23-2)7(20)4-18/h3,6-7,9-11,18,20H,4H2,1-2H3,(H,16,19)(H,21,22)(H4,14,15,17)/t6-,7+,9+,10+,11+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively.|Product information|CAS Number: 203120-17-6|Molecular Weight: 346.34|Formula: C13H22N4O7|Chemical Name: (2R,3R,4S)-4-[(diaminomethylidene)amino]-2-[(1R,2R)-2,3-dihydroxy-1-methoxypropyl]-3-acetamido-3,4-dihydro-2H-pyran-6-carboxylic acid|Smiles: CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](OC)[C@H](O)CO)C(O)=O)N=C(N)N|InChiKey: QNRRHYPPQFELSF-CNYIRLTGSA-N|InChi: InChI=1S/C13H22N4O7/c1-5(19)16-9-6(17-13(14)15)3-8(12(21)22)24-11(9)10(23-2)7(20)4-18/h3,6-7,9-11,18,20H,4H2,1-2H3,(H,16,19)(H,21,22)(H4,14,15,17)/t6-,7+,9+,10+,11+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 5 mg/mL (14.{{Cephalexin} medchemexpress|{Cephalexin} Antibiotic|{Cephalexin} Biological Activity|{Cephalexin} References|{Cephalexin} supplier|{Cephalexin} Autophagy} 44 mM; Need ultrasonic).{{Zafirlukast} site|{Zafirlukast} GPCR/G Protein|{Zafirlukast} Biological Activity|{Zafirlukast} Data Sheet|{Zafirlukast} custom synthesis|{Zafirlukast} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32746667 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Laninamivir (R 125489) inhibits efficiently common oseltamivir-resistant viruses, including those with the ubiquitous His274Tyr substitution. Laninamivir (R 125489) is potent against p57N2, p09N1 and N5 with a similar binding mode to Zanamivir.|Products are for research use only. Not for human use.|