Product Name :
CMP-Sialic acid sodium salt
Description:
CMP-Sialic acid sodium salt (CMP-Neu5Ac sodium salt) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase, the enzyme that initiates sialic acid synthesis. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases.
CAS:
1007117-62-5
Molecular Weight:
636.43
Formula:
C20H30N4NaO16P
Chemical Name:
sodium [5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl 2-carboxy-5-acetamido-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxan-2-yl phosphate
Smiles :
[Na+].CC(=O)NC1C(OC(CC1O)(OP([O-])(=O)OCC1OC(C(O)C1O)N1C=CC(N)=NC1=O)C(O)=O)C(O)C(O)CO
InChiKey:
VFRHSOGUONIUOR-UHFFFAOYSA-M
InChi :
InChI=1S/C20H31N4O16P.Na/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34;/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34);/q;+1/p-1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
CMP-Sialic acid sodium salt (CMP-Neu5Ac sodium salt) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase, the enzyme that initiates sialic acid synthesis. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases.|Product information|CAS Number: 1007117-62-5|Molecular Weight: 636.43|Formula: C20H30N4NaO16P|Chemical Name: sodium [5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl 2-carboxy-5-acetamido-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxan-2-yl phosphate|Smiles: [Na+].{{Netarsudil} web|{Netarsudil} Cytoskeleton|{Netarsudil} Biological Activity|{Netarsudil} Data Sheet|{Netarsudil} custom synthesis|{Netarsudil} Epigenetics} CC(=O)NC1C(OC(CC1O)(OP([O-])(=O)OCC1OC(C(O)C1O)N1C=CC(N)=NC1=O)C(O)=O)C(O)C(O)CO|InChiKey: VFRHSOGUONIUOR-UHFFFAOYSA-M|InChi: InChI=1S/C20H31N4O16P.{{AZD1390} medchemexpress|{AZD1390} ATM/ATR|{AZD1390} Immunology/Inflammation|{AZD1390} Technical Information|{AZD1390} In Vitro|{AZD1390} manufacturer} Na/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34;/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34);/q;+1/p-1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32275462 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|CMP-Sialic acid (CMP-Neu5Ac), the activated form of Neu5Ac, serves as the common activated sugar donor for all the sialyltransferases to transfer a single sialic acid to an acceptor or a growing oligosaccharide chain. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates.|Products are for research use only. Not for human use.|