Product Name :
3, 4-Dehydro Cilostazol
Description:
3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study.
CAS:
73963-62-9
Molecular Weight:
367.44
Formula:
C20H25N5O2
Chemical Name:
6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2-dihydroquinolin-2-one
Smiles :
O=C1C=CC2=CC(=CC=C2N1)OCCCCC1=NN=NN1C1CCCCC1
InChiKey:
GHALECSGOJQOHW-UHFFFAOYSA-N
InChi :
InChI=1S/C20H25N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h9-12,14,16H,1-8,13H2,(H,21,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{TBHQ} site|{TBHQ} MAPK/ERK Pathway|{TBHQ} Biological Activity|{TBHQ} In Vitro|{TBHQ} manufacturer|{TBHQ} Cancer}
Shelf Life:
≥12 months if stored properly.{{Pemigatinib} MedChemExpress|{Pemigatinib} FGFR|{Pemigatinib} Protocol|{Pemigatinib} Purity|{Pemigatinib} supplier|{Pemigatinib} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32445040
Additional information:
3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study.|Product information|CAS Number: 73963-62-9|Molecular Weight: 367.44|Formula: C20H25N5O2|Chemical Name: 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2-dihydroquinolin-2-one|Smiles: O=C1C=CC2=CC(=CC=C2N1)OCCCCC1=NN=NN1C1CCCCC1|InChiKey: GHALECSGOJQOHW-UHFFFAOYSA-N|InChi: InChI=1S/C20H25N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h9-12,14,16H,1-8,13H2,(H,21,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 5 mg/mL (13.61 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|3,4-Dehydro Cilostazol (OPC-13015; Oral; 1 mg/kg GLZ and 10 mg/kg CLZ) has a T1/2 of 3.94 hours, a Cmax of 1.39 μM and an AUC0-24 of 4.69 μg•h/ml. The plasma concentration time profiles of GLZ, CLZ & its active metabolite DCLZ are traceable up to 24 h, 12 h and 12 h respectively by oral administration at 1 mg/kg dose of GLZ and 10 mg/kg CLZ.|Products are for research use only. Not for human use.|