Product Name :
BMS 753
Description:
BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM.
CAS:
215307-86-1
Molecular Weight:
351.40
Formula:
C21H21NO4
Chemical Name:
4-(1,1,3,3-tetramethyl-2-oxo-2,3-dihydro-1H-indene-5-amido)benzoic acid
Smiles :
CC1(C)C2C=C(C=CC=2C(C)(C)C1=O)C(=O)NC1C=CC(=CC=1)C(O)=O
InChiKey:
KFBPBWUZXBYJDG-UHFFFAOYSA-N
InChi :
InChI=1S/C21H21NO4/c1-20(2)15-10-7-13(11-16(15)21(3,4)19(20)26)17(23)22-14-8-5-12(6-9-14)18(24)25/h5-11H,1-4H3,(H,22,23)(H,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM.|Product information|CAS Number: 215307-86-1|Molecular Weight: 351.40|Formula: C21H21NO4|Chemical Name: 4-(1,1,3,3-tetramethyl-2-oxo-2,3-dihydro-1H-indene-5-amido)benzoic acid|Smiles: CC1(C)C2C=C(C=CC=2C(C)(C)C1=O)C(=O)NC1C=CC(=CC=1)C(O)=O|InChiKey: KFBPBWUZXBYJDG-UHFFFAOYSA-N|InChi: InChI=1S/C21H21NO4/c1-20(2)15-10-7-13(11-16(15)21(3,4)19(20)26)17(23)22-14-8-5-12(6-9-14)18(24)25/h5-11H,1-4H3,(H,22,23)(H,24,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (142.Mifanertinib dimaleate Cancer 29 mM; Need ultrasonic).Polyaniline Autophagy |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32877621 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|BMS 753 results in low levels of RARβ transcripts in WT cells, RARγ-/-, but not activates in RARa-/- cells.|Products are for research use only. Not for human use.|