Product Name :
Anti-CD70, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human/Cynomolgus
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-CD70, Human antibody is designed for detecting human CD70 specifically. Anti-CD70, Human antibody is recombinant VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc.Tegaserod Based on ELISA, Anti-CD70, Human antibody reacts with human CD70, and has reactivity with cynomolgus CD70. | Immunogen: Recombinant human CD70 | Host: Alpaca pacous | Isotype: VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation) | Conjugate: Unconjugated | Specificity: Human CD70 | Cross-Reactivity: Cross-reactivity with cynomolgus CD70 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.Relatlimab 5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles), Stable for 12 months at -20°C | Background:CD70 is encoded by a gene, which is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. Using antibody with Fc(mutation), the background from Fc receptors will be eliminated.
Description2 :
Anti-CD70, Human antibody is designed for detecting human CD70 specifically. Anti-CD70, Human antibody is recombinant VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc.PMID:24078122 Based on ELISA, Anti-CD70, Human antibody reacts with human CD70, and has reactivity with cynomolgus CD70.
Immunogen:
Recombinant human CD70
Host :
Alpaca pacous
Isotype:
VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation)
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles), Stable for 12 months at -20°C
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.