Tue. Nov 5th, 2024

Product Name :
NO2-SPDB-sulfo

Description:
NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

CAS:
663598-89-8

Molecular Weight:
451.45

Formula:
C13H13N3O9S3

Chemical Name:
1-({4-[(5-nitropyridin-2-yl)disulfanyl]butanoyl}oxy)-2,5-dioxopyrrolidine-3-sulfonic acid

Smiles :
[O-][N+](=O)C1=CN=C(C=C1)SSCCCC(=O)ON1C(=O)C(CC1=O)S(O)(=O)=O

InChiKey:
AJTQYMNCOAZOGJ-UHFFFAOYSA-N

InChi :
InChI=1S/C13H13N3O9S3/c17-11-6-9(28(22,23)24)13(19)15(11)25-12(18)2-1-5-26-27-10-4-3-8(7-14-10)16(20)21/h3-4,7,9H,1-2,5-6H2,(H,22,23,24)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Tozorakimab} medchemexpress|{Tozorakimab} Interleukin Related|{Tozorakimab} Technical Information|{Tozorakimab} In Vivo|{Tozorakimab} supplier|{Tozorakimab} Autophagy}

Additional information:
NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).{{Enfortumab (anti-Nectin-4)} web|{Enfortumab (anti-Nectin-4)} Immunology/Inflammation|{Enfortumab (anti-Nectin-4)} Biological Activity|{Enfortumab (anti-Nectin-4)} In stock|{Enfortumab (anti-Nectin-4)} manufacturer|{Enfortumab (anti-Nectin-4)} Cancer} |Product information|CAS Number: 663598-89-8|Molecular Weight: 451.45|Formula: C13H13N3O9S3|Chemical Name: 1-({4-[(5-nitropyridin-2-yl)disulfanyl]butanoyl}oxy)-2,5-dioxopyrrolidine-3-sulfonic acid|Smiles: [O-][N+](=O)C1=CN=C(C=C1)SSCCCC(=O)ON1C(=O)C(CC1=O)S(O)(=O)=O|InChiKey: AJTQYMNCOAZOGJ-UHFFFAOYSA-N|InChi: InChI=1S/C13H13N3O9S3/c17-11-6-9(28(22,23)24)13(19)15(11)25-12(18)2-1-5-26-27-10-4-3-8(7-14-10)16(20)21/h3-4,7,9H,1-2,5-6H2,(H,22,23,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:22664133 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|

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