Product Name :
BI-187004
Description:
BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibitor. BI187004/VTP-34072 is being studied for the treatment of type 2 diabetes and metabolic syndrome. In preclinical studies, BI187004/VTP-34072 had a positive impact on multiple cardiovascular and metabolic risk factors associated with metabolic syndrome, which differentiates it from other classes of type 2 diabetes drugs.
CAS:
1303515-32-3
Molecular Weight:
342.39
Formula:
C21H18N4O
Chemical Name:
(4aR, 9aS)-1-(1H-Benzimidazol-6-ylcarbonyl)-2, 3, 4, 4a, 9, 9a-hexahydro-1H-indeno[2, 1-b]pyridine-6-carbonitrile
Smiles :
N#CC1=CC2[C@H]3CCCN([C@H]3CC=2C=C1)C(=O)C1C=C2NC=NC2=CC=1
InChiKey:
VVZNCSHIBODHMZ-UZLBHIALSA-N
InChi :
InChI=1S/C21H18N4O/c22-11-13-3-4-14-10-20-16(17(14)8-13)2-1-7-25(20)21(26)15-5-6-18-19(9-15)24-12-23-18/h3-6,8-9,12,16,20H,1-2,7,10H2,(H,23,24)/t16-,20+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Nirogacestat} MedChemExpress|{Nirogacestat} Apoptosis|{Nirogacestat} Biological Activity|{Nirogacestat} Formula|{Nirogacestat} manufacturer|{Nirogacestat} Autophagy}
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibitor. BI187004/VTP-34072 is being studied for the treatment of type 2 diabetes and metabolic syndrome. In preclinical studies, BI187004/VTP-34072 had a positive impact on multiple cardiovascular and metabolic risk factors associated with metabolic syndrome, which differentiates it from other classes of type 2 diabetes drugs.{{Eribulin} web|{Eribulin} Apoptosis|{Eribulin} Purity & Documentation|{Eribulin} Data Sheet|{Eribulin} custom synthesis|{Eribulin} Epigenetics} |Product information|CAS Number: 1303515-32-3|Molecular Weight: 342.PMID:23795974 39|Formula: C21H18N4O|Synonym:|VTP-34072|Chemical Name: (4aR, 9aS)-1-(1H-Benzimidazol-6-ylcarbonyl)-2, 3, 4, 4a, 9, 9a-hexahydro-1H-indeno[2, 1-b]pyridine-6-carbonitrile|Smiles: N#CC1=CC2[C@H]3CCCN([C@H]3CC=2C=C1)C(=O)C1C=C2NC=NC2=CC=1|InChiKey: VVZNCSHIBODHMZ-UZLBHIALSA-N|InChi: InChI=1S/C21H18N4O/c22-11-13-3-4-14-10-20-16(17(14)8-13)2-1-7-25(20)21(26)15-5-6-18-19(9-15)24-12-23-18/h3-6,8-9,12,16,20H,1-2,7,10H2,(H,23,24)/t16-,20+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|